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PUBLICATIONS
SCIENTIFIC ARTICLES
AS OMBREDANE , VHS ARAUJO, CO BORGES, PL COSTA, MG LANDIM, AC PINHEIRO , Í.O. SZLACHETKA, LEC BENEDITO, LS ESPINDOLA, DJS DIAS, DM OLIVEIRA, JA CHAKER, SW DA SILVA, RB DE AZEVEDO, GA JOANITTI . Nanoemulsion-based systems as a promising approach to enhancing the antitumor activity of pequi oil (Caryocar brasilense Cambess.) in breast cancer cells. Journal of Drug Delivery Science and Technology (2020), DOI: https://doi.org/10.1016/j.jddst.2020.101819
REIS, THAIENE A. ; JACULI, ANA ELISE ; RAMOS, KHELLIDA LV ; SOUZA, PAULO EDUARDO N. ; VEIGA-SOUZA, FABIANE H. ; JOANITTI, GRAZIELLA A. ; AZEVEDO, Ricardo B. ; GRATIERI, TAÍS ; CUNHA-FILHO, MARCILIO ; GELFUSO, GUILHERME M. . Combination of cyclodextrin complexation and iontophoresis as a promising strategy for the cutaneous delivery of aluminum-chloride phthalocyanine in photodynamic therapy. European Journal of Pharmaceutical Sciences , v. 139, p. 105056, 2019. DOI: https://doi.org/10.1016/j.ejps.2019.105056
COELHO, JANAINA MOREIRA ; CAMARGO, NICHOLLAS SERAFIM ; GANASSIN, RAYANE ; ROCHA, MÁRCIA CRISTINA OLIVEIRA ; MERKER, CAROLIN; BÖTTNER, JULIA ; STAR-LOPIS, IRINA ; PY-DANIEL, KAREN RAPP; GARDEN, KATIÚSCIA VIEIRA ; SOUSA, MARCELO HENRIQUE ; OMBREDANE, ALICIA SIMALIE ; JOANITTI, GRAZIELLA ANSELMO ; SILVA, RENATA CARVALHO ; Azevedo, Ricardo Bentes ; LONGO, JOÃO PAULO FIGUEIÓ ; MUEHLMANN, LUIS ALEXANDRE . Oily core/amphiphilic polymer shell nanocapsules change the intracellular fate of doxorubicin in breast cancer cells. Journal of Materials Chemistry B , v. 7, p. 6390-6398, 2019. DOI: https://doi.org/10.1039/C9TB00587K
DOS SANTOS, RAIMUNDA C.; OMBREDANE, ALICIA S. ; SOUZA, JÉSSICA MARIA T.; VASCONCELOS, ANDREANNE G.; PLACIDO, ALEXANDRA; AMORIM, ADRIANY DAS GN; BARBOSA, EDER ALVES; LIMA, FILIPE CDA; ROPKE, CRISTINA D.; ALVES, MICHEL MM; ARCHANGEL, DANIEL DR; CARVALHO, FERNANDO AA; DELERUE-MATOS, CRISTINA; JOANITTI, GRAZIELLA A. ; LEITE, JOSÉ ROBERTO DE SA Lycopene-rich extract from red guava (Psidium guajava L.) displays cytotoxic effect against human breast adenocarcinoma cell line MCF-7 via an apoptotic-like pathway. Food Research International , vol. 105, p. 184-196, 2018. DOI: https://doi.org/10.1016/j.foodres.2017.10.045
REIS, T.; JACULI, A. ; ALVES, R.; GRATIERI, T.; AZEVEDO, RB ; JOANITTI, GA ; GELFUSO, GM ; CUNHA-FILHO, M.. Simple and Selective HPLC-UV/Vis Bioanalytical Method to Determine Aluminum Phthalocyanine Chloride in Skin Permeation Studies. Journal of Analytical Methods in Chemistry , v. 2018, p. 1-7, 2018. DOI: https://doi.org/10.1155/2018/7423764
CAMPELO, YURI ; OMBREDANE, ALICIA ; VASCONCELOS, ANDREANNE ; ALBUQUERQUE, LUCAS ; MOREIRA, DANIEL ; PLACIDO, ALEXANDRA ; ROCHA, JEFFERSON ; HILARION FOKOUE, HAROLD ; YAMAGUCHI, LYDIA ; MAFUD, ANA ; MASCARENHAS, YVONNE ; DELERUE-MATOS, CRISTINA ; BORGES, TATIANA ; JOANITTI, GRAZIELLA ; ARCHANGEL, DANIEL ; KATO, MASSUO ; KUCKELHAUS, SELMA ; SILVA, MARCOS ; MORAES, JOSUÉ ; MILK, JOSEPH. Structure-Activity Relationship of Piplartine and Synthetic Analogues against Schistosoma mansoni and Cytotoxicity to Mammalian Cells. International Journal of Molecular Sciences , v. 19, p. 1802, 2018. DOI: https://doi.org/10.3390/ijms19061802
COELHO, BCP ; SIQUEIRA, ER; OMBREDANE, AS ; JOANITTI, GA ; CHAVES, SB ; DA SILVA, SW ; CHAKER, JA; Long, JPF ; AZEVEDO, RB ; MORAIS, PC ; SOUSA, MH. Maghemite-gold core-shell nanostructures (γ-Fe 2 O 3 @Au) surface-functionalized with aluminum phthalocyanine for multi-task imaging and therapy. RSC ADVANCES: AN International Journal to Further the Chemical Sciences , v. 7, p. 11223-11232, 2017. DOI: https://doi.org/10.1039/C6RA27539G
BARBOSA, EDER ; OLIVEIRA, ANA ; PLACIDO, ALEXANDRA ; SOCODATO, RENATO ; PORTUGAL, CAMILA C. ; MAFUD, ANA CAROLINA ; OMBREDANE, ALICIA S. ; MOREIRA, DANIEL C. ; VALE, NUNO ; BESSA, LUCINDA J. ; JOANITTI, GRAZIELLA A. ; ALVES, CLAUDIA ; GOMES, PAULA ; DELERUE-MATOS, CRISTINA ; MASCARENHAS, YVONNE PRIMERANO ; MARANI, MARIELA M. ; RELVAS, JOÃO B. ; PAINTED, MANUELA ; LEITE, JOSÉ ROBERTO SA . Structure and Function of a Novel Antioxidant Peptide from the Skin of Tropical Frogs. Free Radical Biology and Medicine , v. 115, p. 68-79, 2017. DOI: https://doi.org/10.1016/j.freeradbiomed.2017.11.001
GANASSIN, RAYANE ; MERKER, CAROLIN; RODRIGUES, MOSAR CORRÊA ; GUIMARÃES, NAYARA FELIPE ; SODRÉ, CARINE SAMPAIO CERQUEIRA ; FERREIRA, QUEILA DA SILVA; DA SILVA, SEBASTIÃO WILLIAM ; OMBREDANE, ALICIA SIMALIE ; JOANITTI, GRAZIELLA ANSELMO ; PY-DANIEL, KAREN RAPP; ZHANG, JUAN ; JIANG, CHENG-SHI ; DE MORAIS, PAULO CÉSAR ; MOSINIEWICZ-SZABLEWSKA, EWA ; SUCHOCKI, PIOTR; LONGO, JOÃO PAULO FIGUEIÓ ; MEIJER, JAN ; STAR-LOPIS, IRINA ; DE AZEVEDO, RICARDO BENTES ; MUEHLMANN, LUIS ALEXANDRE . Nanocapsules for the co-delivery of selol and doxorubicin to breast adenocarcinoma 4T1 cells in vitro. Artificial Cells Nanomedicine and Biotechnology , v. 1, p. 1-11, 2017. DOI: https://doi.org/10.1080/21691401.2017.1408020
MILHOMEM-PAIXÃO, SUSANA SUELY RODRIGUES ; FASCINELI, MARIA LUIZA ; MUEHLMANN, LUIS ALEXANDRE ; MELO, KARINA MOTTA ; SALGADO, HUGO LEONARDO CRISÓSTOMO ; JOANITTI, GRAZIELLA ANSELMO ; PIECZARKA, JULIO CESAR ; Azevedo, Ricardo Bentes ; SANTOS, ALBERDAN SILVA ; GRISOLIA, CESAR KOPPE. Andiroba Oil (Carapa guianensis Aublet) Nanoemulsions: Development and Assessment of Cytotoxicity, Genotoxicity, and Hematotoxicity. Journal of Nanomaterials , vol. 2017, p. 1-11, 2017. DOI: https://doi.org/10.1155/2017/4362046
JOANITTI, GA ; GANASSIN, R. ; RODRIGUES, M. ; Long, JPF ; JIANG, C.; GU, J.; PINTO, SML ; SANTOS, MFMA ; AZEVEDO, RB ; Muehlmann, LA. Nanostructured systems for the organelle-specific delivery of anticancer drugs. Mini-Reviews in Medical Chemistry , vol. 16, p. 1-1, 2016. DOI: 10.2174/1389557516666161013104554
QUELEMES, PATRICK V.; DE ARAÚJO, ALYNE R. ; PLACIDO, ALEXANDRA ; DELERUE-MATOS, CRISTINA ; MACIEL, JEANNY S. ; BESSA, LUCINDA ; OMBREDANE, ALICIA S. ; JOANITTI, GRAZIELLA A. ; SOARES, MARIA JOSÉ DOS S. ; EATON, PETER; DA SILVA, DURCILENE A. ; LEITE, JOSÉ ROBERTO SA. Quaternized cashew gum: an anti-staphylococcal and biocompatible cationic polymer for biotechnological applications. Carbohydrate Polymers , v. 157, p. 567-575, 2016. DOI: https://doi.org/10.1016/j.carbpol.2016.10.026
PIBIC
Leonardo Otavio Bispo da Silva. Analysis of β carotene present in buriti oil (Mauritia flexuosa) after formulation process in nanoemulsions. 2019. Scientific Initiation. (Graduating in Chemical Engineering) - University of Brasília. Advisor: Graziella Anselmo Joanitti.
Amanda Fernandes Alves. Physicochemical characterization and evaluation of antimicrobial effect of nanoemulsion based on copaiba oil on Staphylococcus aureus. 2019. Scientific Initiation. (Undergraduate in Biotechnology) - University of Brasilia. Advisor: Graziella Anselmo Joanitti.
Natalia Ornelas Martins . Cytotoxicity of pequi oil and Docetaxel-based nanoemulsions on 4T1 breast cancer cells in vitro. 2019. Scientific Initiation. (Undergraduate in Biotechnology) - University of Brasilia. Advisor: Graziella Anselmo Joanitti.
Amanda Fernandes Alves. Investigation of the antimicrobial effects of a nanoemulsion based on buriti oil on Gram-positive Staphylococcus aureus bacteria, in vitro. 2018. Scientific Initiation. (Undergraduate in Biotechnology) - University of Brasilia. Advisor: Graziella Anselmo Joanitti.
Gabriela Mara Vieira de Souza. Synthesis and characterization of a pequi oil-based nanoemulsion containing the chemotherapeutic Docetaxel. 2018. Scientific Initiation. (Undergraduate in Biotechnology) - University of Brasilia. Advisor: Graziella Anselmo Joanitti.
Leonardo Otávio Bispo da Silva. Evaluation of the oxidation process of buriti oil-based nanoemulsions (Mauritia flexuosa). 2018. Scientific Initiation. (Graduating in Chemical Engineering) - University of Brasília. Advisor: Graziella Anselmo Joanitti.
Beatriz Carvalho de Araújo Oliveira Faria. Effects of pequi oil-based nanoemulsions, modified with PEG and DOTAP, on non-melanoma skin cancer cells, in vitro. 2017. Scientific Initiation. (Undergraduate in Pharmacy) - University of Brasilia. Advisor: Graziella Anselmo Joanitti.
Lucas Campos da Silva. Evaluation of the antioxidant activity of nanoemulsions based on pequi, buriti and açaí oils derived from Brazilian biodiversity. 2017. Scientific Initiation. (Undergraduate in Pharmacy) - University of Brasilia. Advisor: Graziella Anselmo Joanitti.
Patricia Leite Costa. Evaluation of the effects of açaí oil-based nanoemulsions on cell viability, cell cycle and DNA fragmentation of melanoma skin cancer cells, in vitro. 2017. Scientific Initiation. (Undergraduate in Pharmacy) - University of Brasília, National Council for Scientific and Technological Development. Advisor: Graziella Anselmo Joanitti.
Leonardo Otavio Bispo da Silva. Analysis of gene expression by real-time PCR of breast cancer cells after treatment with Pequi (Caryocar brasiliense) oil-based nanoemulsions, in vitro. 2017. Scientific Initiation. (Graduating in Chemical Engineering) - University of Brasília. Advisor: Graziella Anselmo Joanitti.
Beatriz Carvalho de Araujo Oliveira Faria. Effects of Cerrado native fruit oils on non-melanoma skin cancer cells, in vitro. 2015. Scientific Initiation. (Undergraduate in Pharmacy) - University of Brasilia. Advisor: Graziella Anselmo Joanitti.
Lidia Rosa Alves da Silva. Investigation of mechanisms of action of nanostructured Cerrado oil involved in the toxicity of breast cancer cells, in vitro. 2015. Scientific Initiation. (Nursing Student) - University of Brasília, National Council for Scientific and Technological Development. Advisor: Graziella Anselmo Joanitti.
Patricia Leite Costa. Evaluation of cutaneous permeability of oil-carrying polymeric nanoparticles from native fruits of the Cerrado, in vitro. 2015. Scientific Initiation. (Undergraduate in Pharmacy) - University of Brasilia. Advisor: Graziella Anselmo Joanitti.
Victor Hugo Sousa Araujo. Production and characterization of nanoemulsions based on buriti oil (Mauritia flexuosa) associated with chitosan polymers. 2015. Scientific Initiation. (Undergraduate in Pharmacy) - University of Brasilia. Advisor: Graziella Anselmo Joanitti.
Victor Hugo Sousa Araujo. Analysis of the combinatorial effect of acai oil and anacardic acid on the viability of non-melanoma skin cancer cells, in vitro. 2015. Scientific Initiation. (Undergraduate in Pharmacy) - University of Brasilia. Advisor: Graziella Anselmo Joanitti.
Patricia Leite Costa. Evaluation of the effects of buriti oil-based nanoemulsions on the cell cycle and on the DNA fragmentation of breast cancer cells, in vitro. 2015. Scientific Initiation. (Undergraduate in Pharmacy) - University of Brasilia. Advisor: Graziella Anselmo Joanitti.
Marcela Guimaraes Landim. Investigation of the anti-parasitic potential of pequi (Caryocar brasiliense) oil-based nanoemulsions on Trypanosoma cruzi, in vitro. 2015. Scientific Initiation. (Graduating in Biological Sciences) - University of Brasília. Advisor: Graziella Anselmo Joanitti.
Lucas Campos da Silva. Monitoring and standardization of methodology to evaluate the oxidation of nanoemulsions based on natural oils. 2015. Scientific Initiation. (Undergraduate in Pharmacy) - University of Brasilia. Advisor: Graziella Anselmo Joanitti.
Lidia Rosa Alves da Silva. Evaluation of the interaction and cytolocalization of pequi oil-based nanoemulsions in breast cancer cells, in vitro. 2015. Scientific Initiation. (Graduate in Nursing) - University of Brasilia. Advisor: Graziella Anselmo Joanitti.
Beatriz Carvalho de Araujo Oliveira Faria. Studies of polymer insertion (PEG) on the surface of natural oil-based nanoemulsions and their effects on stability and physicochemical parameters. 2015. Scientific Initiation. (Undergraduate in Pharmacy) - University of Brasilia. Advisor: Graziella Anselmo Joanitti.
Clarissa Oliveira da Rocha. Effects of native fruit oils from the Cerrado, in free or nanostructured form, on breast cancer cells, in vitro. 2014. Scientific Initiation. (Graduate in Nursing) - University of Brasilia. Advisor: Graziella Anselmo Joanitti.
Victor Hugo Sousa Araujo. Development and characterization of nanoemulsions based on oils from native fruits of the Cerrado associated with chitosan polymers. 2014. Scientific Initiation . (Undergraduate in Pharmacy) - University of Brasilia. Advisor: Graziella Anselmo Joanitti.
Lidia Rosa Alves da Silva. Biocompatibility analysis of magnetic nanoparticles in mammalian cells. 2014. Scientific Initiation. (Graduate in Nursing) - University of Brasilia. Advisor: Graziella Anselmo Joanitti.
Patricia Leite Costa. Development and characterization of polymeric nanocapsules. 2014. Scientific Initiation. (Undergraduate in Pharmacy) - University of Brasília, Coordination for the Improvement of Higher Education Personnel. Advisor: Graziella Anselmo Joanitti.
MASTER'S DISSERTATIONS
Patricia Leite Costa. Evaluation of the effects of nanoemulsions based on acai oil and anacardic acid in the prevention of cancer and in the migration and invasion of melanoma skin cancer, in vitro. 2020. Dissertation (Master's in Health Sciences and Technologies) - University of Brasília. Advisor: Graziella Anselmo Joanitti.
Beatriz Carvalho de Araújo Oliveira Faria. Association of folic acid on the surface of pequi oil-based nanoemulsion and investigation of its effects on breast cancer cells in vitro. 2020. Dissertation (Master's in Nanoscience and Nanobiotechnology) - University of Brasília. Advisor: Graziella Anselmo Joanitti.
Lucas Campos da Silva. Association of free and nanostructured resveratrol and açaí (Euterpe oleracea Mart.) oil in the treatment of non-melanoma skin cancer, in vitro. 2020. Dissertation (Master's in Health Sciences and Technologies) - University of Brasília. Advisor: Graziella Anselmo Joanitti.
Marcela Guimaraes Landim. Study of the antibacterial activity of a nanoemulsion based on copaiba oil (Copaifera officinalis) and its combination with anacardic acid. 2019. Dissertation (Master's in Nanoscience and Nanobiotechnology) - University of Brasília, Coordination for the Improvement of Higher Education Personnel. Advisor: Graziella Anselmo Joanitti.
Thamara Rodrigues Alexandre. Therapeutic effects of anacardic acid associated with nanoemulsions based on acai oil (Euterpe oleracea Mart.) in the treatment of breast cancer cells with different metastatic potential, in vitro . 2018. Dissertation (Master's in Nanoscience and Nanobiotechnology) - University of Brasília. Advisor: Graziella Anselmo Joanitti
Marina Carvalho Sampaio. Development and characterization of Buriti ( Mauritia flexuosa ) oil-based nanoemulsions for the in vitro treatment of breast cancer. 2017. Dissertation (Master's in Nanoscience and Nanobiotechnology) - University of Brasília. Advisor: Graziella Anselmo Joanitti
Henrique Loback Lopes de Araújo. Effects of combinations between anacardic acid derived from cashew nuts ( Anacardium occidentale ) and açaí oil ( Euterpe oleracea Mart.), free or nanostructured, in the of non-melanoma skin cancer, in vitro . 2017. Dissertation (Master's in Nanoscience and Nanobiotechnology) - University of Brasília. Advisor: Graziella Anselmo Joanitti
Alicia Simalie Ombredane. Green synthesis of silver nanoparticles from aqueous extract of Curcuma longa tuber associated with chitosan and evaluation of antitumor activity in vitro in non-melanoma skin cancer (lineage A431). 2016. Dissertation (Master's in Nanoscience and Nanobiotechnology) - University of Brasília. Advisor: Graziella Anselmo Joanitti
COMPLETION OF COURSE WORK
Patricia Leite Costa. Evaluation of the effects of açaí oil-based nanoemulsions on cell viability, cell cycle and DNA fragmentation of melanoma skin cancer cells, in vitro . 2017. Course Completion Work . (Graduate in Pharmacy) - University of Brasilia. Advisor: Graziella Anselmo Joanitti
Lucas Campos da Silva. Monitoring and evaluation of oxidation and antioxidant activity of nanoemulsions based on natural oils. 2017. Course Completion Work . (Graduate in Pharmacy) - University of Brasilia. Advisor: Graziella Anselmo Joanitti
Beatriz Carvalho de Araújo Oliveira Faria. Polyethylene glycol (PEG) polymer incorporation in pequi ( Caryocar brasiliense ) oil based nanoemulsions: formulation, characterization and effects on non-melanoma skin cancer cells. 2017. Course Completion Work . (Graduate in Pharmacy) - University of Brasilia. Advisor: Graziella Anselmo Joanitti
Victor Hugo Sousa Araujo. Pequi ( Caryocar brasiliense ) oil-based nanoemulsions: synthesis, characterization and evaluation of the effect on breast carcinoma cells. 2016. Course Completion Work . (Graduate in Pharmacy) - University of Brasilia. Advisor: Graziella Anselmo Joanitti
Lidia Rosa Alves Da Silva. Investigation and evaluation of mechanisms of action of pequi oil-based nanoemulsions in breast cancer cells, in vitro . 2016. Course Completion Work . (Nursing Graduate) - University of Brasilia. Advisor: Graziella Anselmo Joanitti
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